G Proteins Gα(i1/3) Are Critical Targets for Bordetella pertussis Toxin-Induced Vasoactive Amine Sensitization

Pertussis toxin (PTX) is an AB5-type exotoxin produced by the bacterium Bordetella pertussis, the causative agent of whooping cough. In vivo intoxication with PTX elicits a variety of immunologic and inflammatory responses, including vasoactive amine sensitization (VAAS) to histamine (HA), serotonin...

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Detalhes bibliográficos
Main Authors: Diehl, Sean A., McElvany, Benjamin, Noubade, Rajkumar, Seeberger, Nathan, Harding, Brock, Spach, Karen, Teuscher, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911370/
https://ncbi.nlm.nih.gov/pubmed/24478091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00971-13
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