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In Silico Rational Design and Systems Engineering of Disulfide Bridges in the Catalytic Domain of an Alkaline α-Amylase from Alkalimonas amylolytica To Improve Thermostability

High thermostability is required for alkaline α-amylases to maintain high catalytic activity under the harsh conditions used in textile production. In this study, we attempted to improve the thermostability of an alkaline α-amylase from Alkalimonas amylolytica through in silico rational design and s...

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Main Authors: Liu, Long, Deng, Zhuangmei, Yang, Haiquan, Li, Jianghua, Shin, Hyun-dong, Chen, Rachel R., Du, Guocheng, Chen, Jian
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911192/
https://ncbi.nlm.nih.gov/pubmed/24212581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03045-13
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