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Amino-4-Imidazolecarboxamide Ribotide Directly Inhibits Coenzyme A Biosynthesis in Salmonella enterica
Aminoimidazole carboxamide ribotide (AICAR) is a purine biosynthetic intermediate and a by-product of histidine biosynthesis. In bacteria, yeast, and humans, accumulation of AICAR has been shown to affect an array of cellular processes by both direct and indirect mechanisms. In purine biosynthesis,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3911171/ https://ncbi.nlm.nih.gov/pubmed/24296672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01087-13 |
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