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Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.

Microinjection of foreign DNA into fertilized mammalian eggs is a convenient means of introducing genes into the germ line. Some of the more important parameters that influence successful integration of foreign DNA into mouse chromosomes are described. The effects of DNA concentration, size, and for...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Brinster, R L, Chen, H Y, Trumbauer, M E, Yagle, M K, Palmiter, R D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391116/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3892534/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.13.4438
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