Genetic transformation of mouse embryos by microinjection of purified DNA.

A recombinant plasmid composed of segments of herpes simplex virus and simian virus 40 viral DNA inserted into the bacterial plasmid pBR322 was microinjected into pronuclei of fertilized mouse oocytes. The embryos were implanted in the oviducts of pseudopregnant females and allowed to develop to ter...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gordon, J W, Scangos, G A, Plotkin, D J, Barbosa, J A, Ruddle, F H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1980
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6261253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.12.7380
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