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Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules.

We examined the fate of DNA microinjected into nuclei of cultured mammalian cells. The sequence composition and the physical form of the vector carrying the selectable gene affected the efficiency of DNA-mediated transformation. Introduction of sequences near the simian virus 40 origin of DNA replic...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Folger, K R, Wong, E A, Wahl, G, Capecchi, M R
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1982
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369942/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6298598/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.11.1372
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