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Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules.

We examined the fate of DNA microinjected into nuclei of cultured mammalian cells. The sequence composition and the physical form of the vector carrying the selectable gene affected the efficiency of DNA-mediated transformation. Introduction of sequences near the simian virus 40 origin of DNA replic...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Folger, K R, Wong, E A, Wahl, G, Capecchi, M R
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369942/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6298598/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.11.1372-1387.1982
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