Interaction of Apurinic/Apyrimidinic Endonucleases Nfo and ExoA with the DNA Integrity Scanning Protein DisA in the Processing of Oxidative DNA Damage during Bacillus subtilis Spore Outgrowth

Oxidative stress-induced damage, including 8-oxo-guanine and apurinic/apyrimidinic (AP) DNA lesions, were detected in dormant and outgrowing Bacillus subtilis spores lacking the AP endonucleases Nfo and ExoA. Spores of the Δnfo exoA strain exhibited slightly slowed germination and greatly slowed out...

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Bibliografische gegevens
Hoofdauteurs: Campos, Silvia S., Ibarra-Rodriguez, Juan R., Barajas-Ornelas, Rocío C., Ramírez-Guadiana, Fernando H., Obregón-Herrera, Armando, Setlow, Peter, Pedraza-Reyes, Mario
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911150/
https://ncbi.nlm.nih.gov/pubmed/24244006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01259-13
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