Interaction of Apurinic/Apyrimidinic Endonucleases Nfo and ExoA with the DNA Integrity Scanning Protein DisA in the Processing of Oxidative DNA Damage during Bacillus subtilis Spore Outgrowth

Oxidative stress-induced damage, including 8-oxo-guanine and apurinic/apyrimidinic (AP) DNA lesions, were detected in dormant and outgrowing Bacillus subtilis spores lacking the AP endonucleases Nfo and ExoA. Spores of the Δnfo exoA strain exhibited slightly slowed germination and greatly slowed out...

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Autori principali: Campos, Silvia S., Ibarra-Rodriguez, Juan R., Barajas-Ornelas, Rocío C., Ramírez-Guadiana, Fernando H., Obregón-Herrera, Armando, Setlow, Peter, Pedraza-Reyes, Mario
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911150/
https://ncbi.nlm.nih.gov/pubmed/24244006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01259-13
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