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A New Reduced Human-Mouse Somatic Cell Hybrid Containing the Human Gene for Adenine Phosphoribosyltransferase

A system that selects for the gene directing synthesis of the enzyme adenine phosphoribosyltransferase (APRT) uses the antibiotic alanosine to prevent endogenous synthesis of adenylic acid. With the aid of this system, a new series of human-mouse hybrids has been prepared between wild type human dip...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kusano, Toshihisa, Long, Cedric, Green, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391107/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5276304/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.1.82
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