Long-Incubation-Time Gamma Interferon Release Assays in Response to Purified Protein Derivative, ESAT-6, and/or CFP-10 for the Diagnosis of Mycobacterium tuberculosis Infection in Children

The diagnosis of childhood active tuberculosis (aTB) and latent Mycobacterium tuberculosis (M. tuberculosis) infection (LTBI) remains a challenge, and the replacement of tuberculin skin tests (TST) with commercialized gamma interferon (IFN-γ) release assays (IGRA) is not currently recommended. Two h...

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Main Authors: Schepers, K., Mouchet, F., Dirix, V., De Schutter, I., Jotzo, K., Verscheure, V., Geurts, P., Singh, M., Van Vooren, J. P., Mascart, F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Diagnostic Laboratory Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910945/
https://ncbi.nlm.nih.gov/pubmed/24152386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00525-13
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