Intramuscular Delivery of Adenovirus Serotype 5 Vector Expressing Humanized Protective Antigen Induces Rapid Protection against Anthrax That May Bypass Intranasally Originated Preexisting Adenovirus Immunity

Developing an effective anthrax vaccine that can induce a rapid and sustained immune response is a priority for the prevention of bioterrorism-associated anthrax infection. Here, we developed a recombinant replication-deficient adenovirus serotype 5-based vaccine expressing the humanized protective...

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Detalhes bibliográficos
Main Authors: Wu, Shipo, Zhang, Zhe, Yu, Rui, Zhang, Jun, Liu, Ying, Song, Xiaohong, Yi, Shaoqiong, Liu, Ju, Chen, Jianqin, Yin, Ying, Xu, Junjie, Hou, Lihua, Chen, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910935/
https://ncbi.nlm.nih.gov/pubmed/24307239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00560-13
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