Moxifloxacin Population Pharmacokinetics and Model-Based Comparison of Efficacy between Moxifloxacin and Ofloxacin in African Patients

Pharmacokinetic exposure and the MIC of fluoroquinolones are important determinants of their efficacy against Mycobacterium tuberculosis. Population modeling was used to describe the steady-state plasma pharmacokinetics of moxifloxacin in 241 tuberculosis (TB) patients in southern Africa. Monte Carl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zvada, Simbarashe P., Denti, Paolo, Sirgel, Frederick A., Chigutsa, Emmanuel, Hatherill, Mark, Charalambous, Salome, Mungofa, Stanley, Wiesner, Lubbe, Simonsson, Ulrika S. H., Jindani, Amina, Harrison, Thomas, McIlleron, Helen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910772/
https://ncbi.nlm.nih.gov/pubmed/24189253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01478-13
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge