Biological Cost of Different Mechanisms of Colistin Resistance and Their Impact on Virulence in Acinetobacter baumannii

Two mechanisms of resistance to colistin have been described in Acinetobacter baumannii. One involves complete loss of lipopolysaccharide (LPS), resulting from mutations in lpxA, lpxC, or lpxD, and the second is associated with phosphoethanolamine addition to LPS, mediated through mutations in pmrAB...

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Main Authors: Beceiro, Alejandro, Moreno, Antonio, Fernández, Nathalie, Vallejo, Juán A., Aranda, Jesús, Adler, Ben, Harper, Marina, Boyce, John D., Bou, Germán
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910726/
https://ncbi.nlm.nih.gov/pubmed/24189257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01597-13
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