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Structural inhibition of the colicin D tRNase by the tRNA-mimicking immunity protein

Colicins are toxins secreted by Escherichia coli in order to kill their competitors. Colicin D is a 75 kDa protein that consists of a translocation domain, a receptor-binding domain and a cytotoxic domain, which specifically cleaves the anticodon loop of all four tRNA(Arg) isoacceptors, thereby inac...

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Detalhes bibliográficos
Main Authors: Graille, Marc, Mora, Liliana, Buckingham, Richard H, van Tilbeurgh, Herman, de Zamaroczy, Miklos
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC391069/
https://ncbi.nlm.nih.gov/pubmed/15014439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600162
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