Structural inhibition of the colicin D tRNase by the tRNA-mimicking immunity protein

Colicins are toxins secreted by Escherichia coli in order to kill their competitors. Colicin D is a 75 kDa protein that consists of a translocation domain, a receptor-binding domain and a cytotoxic domain, which specifically cleaves the anticodon loop of all four tRNA(Arg) isoacceptors, thereby inac...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Graille, Marc, Mora, Liliana, Buckingham, Richard H, van Tilbeurgh, Herman, de Zamaroczy, Miklos
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
Fag:
Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391069/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15014439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600162
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