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Importin α associates with membranes and participates in nuclear envelope assembly in vitro

Importin α is well known as an adaptor that functions with Importin β in the nuclear import of proteins containing specific nuclear localization signals (NLSs). We show here that either an excess or a lack of Importin α blocks nuclear envelope (NE) assembly in vitro, and our data suggest that solubl...

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Detalhes bibliográficos
Main Authors: Hachet, Virginie, Köcher, Thomas, Wilm, Matthias, Mattaj, Iain W
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC391064/
https://ncbi.nlm.nih.gov/pubmed/15014441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600154
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