Chromatin-bound NLS proteins recruit membrane vesicles and nucleoporins for nuclear envelope assembly via importin-α/β

The mechanism for nuclear envelope (NE) assembly is not fully understood. Importin-β and the small GTPase Ran have been implicated in the spatial regulation of NE assembly process. Here we report that chromatin-bound NLS (nuclear localization sequence) proteins provide docking sites for the NE precu...

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Bibliographische Detailangaben
Hauptverfasser: Lu, Quanlong, Lu, Zhigang, Liu, Qinying, Guo, Li, Ren, He, Fu, Jingyan, Jiang, Qing, Clarke, Paul R, Zhang, Chuanmao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494395/
https://ncbi.nlm.nih.gov/pubmed/22847741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.113
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