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Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB

p140 Ras-GRF1 and p130 Ras-GRF2 constitute a family of calcium/calmodulin-regulated guanine–nucleotide exchange factors that activate the Ras GTPases. Studies on mice lacking these exchange factors revealed that both p140 Ras-GRF1 and p130 Ras-GRF2 couple NMDA glutamate receptors (NMDARs) to the act...

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Bibliografiska uppgifter
Huvudupphovsmän: Tian, Xuejun, Gotoh, Takaya, Tsuji, Kiyoshi, Lo, Eng H, Huang, Su, Feig, Larry A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2004
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC391062/
https://ncbi.nlm.nih.gov/pubmed/15029245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600151
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