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Long-Term Potentiation in the CA1 Hippocampus Induced by NR2A Subunit-Containing NMDA Glutamate Receptors Is Mediated by Ras-GRF2/Erk Map Kinase Signaling
BACKGROUND: NMDA-type glutamate receptors (NMDARs) are major contributors to long-term potentiation (LTP), a form of synaptic plasticity implicated in the process of learning and memory. These receptors consist of calcium-permeating NR1 and multiple regulatory NR2 subunits. A majority of studies sho...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908693/ https://ncbi.nlm.nih.gov/pubmed/20661302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011732 |
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