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Oncogenes induce a vimentin filament collapse mediated by HDAC6 that is linked to cell stiffness

Oncogenes deregulate fundamental cellular functions, which can lead to development of tumors, tumor-cell invasion, and metastasis. As the mechanical properties of cells govern cell motility, we hypothesized that oncogenes promote cell invasion by inducing cytoskeletal changes that increase cellular...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Rathje, Li-Sophie Z., Nordgren, Niklas, Pettersson, Torbjörn, Rönnlund, Daniel, Widengren, Jerker, Aspenström, Pontus, Gad, Annica K. B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910606/
https://ncbi.nlm.nih.gov/pubmed/24474778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300238111
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