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Release of protein A from the cell wall of Staphylococcus aureus

Staphylococcal protein A (SpA) is anchored to the cell wall envelope of Staphylococcus aureus by sortase A, which links the threonyl (T) of its C-terminal LPXTG motif to peptidoglycan cross-bridges (i.e., Gly(5)). SpA binds the Fcγ domains of IgG and protects staphylococci from opsonophagocytic clea...

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Autors principals: Becker, Samuel, Frankel, Matthew B., Schneewind, Olaf, Missiakas, Dominique
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910568/
https://ncbi.nlm.nih.gov/pubmed/24434550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317181111
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