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Type I interferon signature is high in lupus and neuromyelitis optica but low in multiple sclerosis

OBJECTIVE: Neuromyelitis optica (NMO) is characterized by selective inflammation of the spinal cord and optic nerves but is distinct from multiple sclerosis (MS). Interferon (IFN)-β mitigates disease activity in MS, but is controversial in NMO, with a few reports of disease worsening after IFN-β the...

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Detalhes bibliográficos
Main Authors: Feng, Xuan, Reder, Nicholas P., Yanamandala, Mounica, Hill, Addie, Franek, Beverly S., Niewold, Timothy B., Reder, Anthony T., Javed, Adil
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910514/
https://ncbi.nlm.nih.gov/pubmed/22036215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2011.09.032
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