Genome-wide Association Study Identifies Two Susceptibility Loci for Osteosarcoma

Osteosarcoma is the most common primary bone malignancy of adolescents and young adults. In order to better understand the genetic etiology of osteosarcoma, we performed a multi-stage genome-wide association study (GWAS) consisting of 941 cases and 3,291 cancer-free adult controls of European ancest...

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Autori principali: Savage, Sharon A., Mirabello, Lisa, Wang, Zhaoming, Gastier-Foster, Julie M., Gorlick, Richard, Khanna, Chand, Flanagan, Adrienne M., Tirabosco, Roberto, Andrulis, Irene L., Wunder, Jay S., Gokgoz, Nalan, Patiño-Garcia, Ana, Sierrasesúmaga, Luis, Lecanda, Fernando, Kurucu, Nilgün, Ilhan, Inci Ergurhan, Sari, Neriman, Serra, Massimo, Hattinger, Claudia, Picci, Piero, Spector, Logan, Barkauskas, Donald A., Marina, Neyssa, de Toledo, Silvia Regina Caminada, Petrilli, Antonio S., Amary, Maria Fernanda, Halai, Dina, Thomas, David M., Douglass, Chester, Meltzer, Paul S., Jacobs, Kevin, Chung, Charles C., Berndt, Sonja I., Purdue, Mark P., Caporaso, Neil E., Tucker, Margaret, Rothman, Nathaniel, Landi, Maria Teresa, Silverman, Debra T., Kraft, Peter, Hunter, David J., Malats, Nuria, Kogevinas, Manolis, Wacholder, Sholom, Troisi, Rebecca, Helman, Lee, Fraumeni, Joseph F., Yeager, Meredith, Hoover, Robert N., Chanock, Stephen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910497/
https://ncbi.nlm.nih.gov/pubmed/23727862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2645
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