KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis

BACKGROUND: Fibroblast activation plays a critical role in diabetic nephropathy (DN). The Ca(2+)-activated K(+) channel KCa3.1 mediates cellular proliferation of many cell types including fibroblasts. KCa3.1 has been reported to be a potential molecular target for pharmacological intervention in a d...

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Autors principals: Huang, Chunling, Shen, Sylvie, Ma, Qing, Gill, Anthony, Pollock, Carol A., Chen, Xin-Ming
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910344/
https://ncbi.nlm.nih.gov/pubmed/24166472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gft431
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