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KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis
BACKGROUND: Fibroblast activation plays a critical role in diabetic nephropathy (DN). The Ca(2+)-activated K(+) channel KCa3.1 mediates cellular proliferation of many cell types including fibroblasts. KCa3.1 has been reported to be a potential molecular target for pharmacological intervention in a d...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910344/ https://ncbi.nlm.nih.gov/pubmed/24166472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gft431 |
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