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Bone Morphogenetic Protein-2 Desensitizes MC3T3-E1 Osteoblastic Cells to Estrogen Through Transcriptional Downregulation of Estrogen Receptor 1
BACKGROUND: Estrogens exert preferable effects on bone metabolism through two estrogen receptors (ERs), ER1 and ER2, which activate the transcription of a set of genes as ligand-dependent transcription factors. Thus, growth factors and hormones which modulate ER expression in the bone, if any, may p...
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| Formato: | Artigo |
| Idioma: | Inglês |
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The Korean Society for Bone and Mineral Research
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910307/ https://ncbi.nlm.nih.gov/pubmed/24524062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11005/jbm.2013.20.2.83 |
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