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The structural mechanism of KCNH-channel regulation by the eag domain
The KCNH voltage-dependent potassium channels (ether-á-go-go, EAG; EAG-related gene, ERG; EAG-like channels, ELK) are important regulators of cellular excitability(1-3) and have key roles in diseases such as cardiac long QT syndrome type 2 (LQT2)(4), epilepsy(5), schizophrenia(6) and cancer(7). The...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910112/ https://ncbi.nlm.nih.gov/pubmed/23975098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12487 |
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