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A likelihood ratio test for genomewide association under genetic heterogeneity
Most existing association tests for genome-wide association studies (GWAS) fail to account for genetic heterogeneity. Zhou and Pan proposed a binomial mixture model based association test to account for the possible genetic heterogeneity in case-control studies. The idea is elegant, however, the pro...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910100/ https://ncbi.nlm.nih.gov/pubmed/23362943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12005 |
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