Efficient insertion of genes into the mouse germ line via retroviral vectors.

We present a general strategy for the efficient insertion of recombinant retroviral vector DNA into the mouse germ line via infection of preimplantation mouse embryos. Transgenic mice were generated that harbor a replication-competent recombinant retrovirus (delta Mo + Py M-MuLV) that lacks the Molo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: van der Putten, H, Botteri, F M, Miller, A D, Rosenfeld, M G, Fan, H, Evans, R M, Verma, I M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391009/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3862122/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.18.6148
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