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Genome-wide assessments reveal extremely high levels of polymorphism of two active families of mouse endogenous retroviral elements.

Endogenous retroviral elements (ERVs) in mice are significant genomic mutagens, causing approximately 10% of all reported spontaneous germ line mutations in laboratory strains. The majority of these mutations are due to insertions of two high copy ERV families, the IAP and ETn/MusD elements. This si...

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Principais autores: Ying Zhang, Irina A Maksakova, Liane Gagnier, Louie N van de Lagemaat, Dixie L Mager
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2008-02-01
Serier:PLoS Genetics
Online adgang:http://europepmc.org/articles/PMC2265474?pdf=render
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