The Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Relationships of Evacetrapib Administered as Monotherapy or in Combination With Statins

Evacetrapib is a novel cholesteryl ester transfer protein (CETP) inhibitor currently being evaluated in a late-stage cardiovascular outcome trial. Using population-based models, we analyzed evacetrapib concentration data along with high-density lipoprotein cholesterol (HDL-C) and low-density lipopro...

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Main Authors: Friedrich, S, Kastelein, J J P, James, D, Waterhouse, T, Nissen, S E, Nicholls, S J, Krueger, K A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910017/
https://ncbi.nlm.nih.gov/pubmed/24452615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2013.70
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