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Utility of network integrity methods in therapeutic target identification

Analysis of the biological gene networks involved in a disease may lead to the identification of therapeutic targets. Such analysis requires exploring network properties, in particular the importance of individual network nodes (i.e., genes). There are many measures that consider the importance of n...

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Bibliografiske detaljer
Main Authors: Peng, Qian, Schork, Nicholas J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909879/
https://ncbi.nlm.nih.gov/pubmed/24550933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00012
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