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Application of the mini-Mu-phage for target-sequence-specific insertional mutagenesis of the herpes simplex virus genome.

An earlier technique for insertional mutagenesis of large viral genomes involved the insertion of the thymidine kinase (TK) gene at a specific target site, cotransfection of the fragment carrying the insertion with the intact viral genome, and selection of the progeny for viral recombinants expressi...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Jenkins, F J, Casadaban, M J, Roizman, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1985
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2991892/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.14.4773
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