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Application of the mini-Mu-phage for target-sequence-specific insertional mutagenesis of the herpes simplex virus genome.

An earlier technique for insertional mutagenesis of large viral genomes involved the insertion of the thymidine kinase (TK) gene at a specific target site, cotransfection of the fragment carrying the insertion with the intact viral genome, and selection of the progeny for viral recombinants expressi...

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Detalles Bibliográficos
Main Authors: Jenkins, F J, Casadaban, M J, Roizman, B
Formato: Artigo
Idioma:Inglês
Publicado: 1985
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC390987/
https://ncbi.nlm.nih.gov/pubmed/2991892
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