Application of the mini-Mu-phage for target-sequence-specific insertional mutagenesis of the herpes simplex virus genome.
An earlier technique for insertional mutagenesis of large viral genomes involved the insertion of the thymidine kinase (TK) gene at a specific target site, cotransfection of the fragment carrying the insertion with the intact viral genome, and selection of the progeny for viral recombinants expressi...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1985
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390987/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2991892/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.14.4773 |
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