AUTOMATED QUANTIFICATION OF ZEBRAFISH TAIL DEFORMATION FOR HIGH-THROUGHPUT DRUG SCREENING

Zebrafish (Danio rerio) is an important vertebrate model organism in biomedical research thanks to its ease of handling and translucent body, enabling in vivo imaging. Zebrafish embryos undergo spinal deformation upon exposure to chemical agents that inhibit DNA repair. Automated image-based quantif...

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Hlavní autoři: Ishaq, Omer, Negri, Joseph, Bray, Mark-Anthony, Pacureanu, Alexandra, Peterson, Randall T., Wählby, Carolina
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909804/
https://ncbi.nlm.nih.gov/pubmed/24499782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/ISBI.2013.6556621
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