Automated Reporter Quantification In Vivo: High-Throughput Screening Method for Reporter-Based Assays in Zebrafish

Reporter-based assays underlie many high-throughput screening (HTS) platforms, but most are limited to in vitro applications. Here, we report a simple whole-organism HTS method for quantifying changes in reporter intensity in individual zebrafish over time termed, Automated Reporter Quantification i...

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Main Authors: Walker, Steven L., Ariga, Junko, Mathias, Jonathan R., Coothankandaswamy, Veena, Xie, Xiayang, Distel, Martin, Köster, Reinhard W., Parsons, Michael J., Bhalla, Kapil N., Saxena, Meera T., Mumm, Jeff S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251595/
https://ncbi.nlm.nih.gov/pubmed/22238673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029916
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