Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia

Nuclear receptors are transcription factors that regulate diverse cellular processes. In canonical activation, ligand availability is sufficient to produce receptor binding, entraining downstream signaling. The mineralocorticoid receptor (MR) is normally activated by aldosterone, which is produced i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shibata, Shigeru, Rinehart, Jesse, Zhang, Junhui, Moeckel, Gilbert, Castañeda-Bueno, María, Stiegler, Amy L., Boggon, Titus J., Gamba, Gerardo, Lifton, Richard P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909709/
https://ncbi.nlm.nih.gov/pubmed/24206662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.10.005
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