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Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia
Nuclear receptors are transcription factors that regulate diverse cellular processes. In canonical activation, ligand availability is sufficient to produce receptor binding, entraining downstream signaling. The mineralocorticoid receptor (MR) is normally activated by aldosterone, which is produced i...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3909709/ https://ncbi.nlm.nih.gov/pubmed/24206662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.10.005 |
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