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P-glycoprotein induction by breast milk attenuates intestinal inflammation in experimental necrotizing enterocolitis
P-glycoprotein (Pgp), a product of the multi-drug resistance gene MDR1a, is a broad specificity efflux ATP cassette transmembrane transporter that is predominantly expressed in epithelial tissues. Because mdr1a(−/−) mice tend to develop spontaneous colitis in bacteria-dependent manner, Pgp is believ...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3909679/ https://ncbi.nlm.nih.gov/pubmed/21788941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.113 |
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