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The NHR-8 Nuclear Receptor Regulates Cholesterol and Bile Acid Homeostasis in C. elegans
Hormone-gated nuclear receptors (NRs) are conserved transcriptional regulators of metabolism, reproduction and homeostasis. Here we show that C. elegans NHR-8 NR, a homolog of vertebrate Liver-X and Vitamin-D receptors, regulates nematode cholesterol balance, fatty acid desaturation, apolipoprotein...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3909615/ https://ncbi.nlm.nih.gov/pubmed/23931753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.07.007 |
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