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Impact of aging in cancer immunotherapy: The importance of using accurate preclinical models

Cancer immunotherapy holds great promise, yet its efficacy and applicability can be hampered by the rise of systemic toxicities. We have recently shown that the lethal side effects of cancer immunotherapy are markedly exacerbated with aging. Blocking tumor necrosis factor α or macrophages can allevi...

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Bibliografiske detaljer
Main Authors: Bouchlaka, Myriam N, Murphy, William J
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909540/
https://ncbi.nlm.nih.gov/pubmed/24498569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27186
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