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Impact of aging in cancer immunotherapy: The importance of using accurate preclinical models

Cancer immunotherapy holds great promise, yet its efficacy and applicability can be hampered by the rise of systemic toxicities. We have recently shown that the lethal side effects of cancer immunotherapy are markedly exacerbated with aging. Blocking tumor necrosis factor α or macrophages can allevi...

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Autori principali: Bouchlaka, Myriam N, Murphy, William J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909540/
https://ncbi.nlm.nih.gov/pubmed/24498569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27186
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