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Multistep transformation by defined fragments of herpes simplex virus type 2 DNA: oncogenic region and its gene product.

Diploid Syrian hamster embryo cells transfected with Bgl II C fragment of herpes simplex virus type 2 DNA acquired a neoplastic phenotype. Cultures transfected with its left-hand 64% subclone EcoRI/HindIII fragment AE (0.419-0.525 map unit) grew into established but nontumorigenic lines. Transfectio...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hayashi, Y, Iwasaka, T, Smith, C C, Aurelian, L, Lewis, G K, Ts'o, P O
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390942/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3001705/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8493
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