DNA amplification and neoplastic transformation mediated by a herpes simplex DNA fragment containing cell-related sequences.

The transforming potential of the herpes simplex virus type 2 (HSV-2) BamHI fragment E (map position 0.533-0.583) encoding the 140-kDa ribonucleotide reductase was assayed by transfection in established Rat-2 cells. Foci of refractile, morphologically distinguishable cells were induced at lower effi...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Jariwalla, R J, Tanczos, B, Jones, C, Ortiz, J, Salimi-Lopez, S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323159/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3006067/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.6.1738
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