DNA amplification and neoplastic transformation mediated by a herpes simplex DNA fragment containing cell-related sequences.
The transforming potential of the herpes simplex virus type 2 (HSV-2) BamHI fragment E (map position 0.533-0.583) encoding the 140-kDa ribonucleotide reductase was assayed by transfection in established Rat-2 cells. Foci of refractile, morphologically distinguishable cells were induced at lower effi...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1986
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323159/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3006067/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.6.1738 |
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