A four-marker signature of TNF-RII, TGF-α, TIMP-1 and CRP is prognostic of worse survival in high-risk surgically resected melanoma

BACKGROUND: E1694 tested GM2-KLH-QS21 vaccine versus high-dose interferon-α2b (HDI) as adjuvant therapy for operable stage IIB-III melanoma. We tested banked serum specimens from patients in the vaccine arm of E1694 for prognostic biomarkers. METHODS: Aushon Multiplex Platform was used to quantitate...

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Bibliographic Details
Main Authors: Tarhini, Ahmad A, Lin, Yan, Yeku, Oladapo, LaFramboise, William A, Ashraf, Madeeha, Sander, Cindy, Kirkwood, John M, Lee, Sandra
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909384/
https://ncbi.nlm.nih.gov/pubmed/24457057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-19
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