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Modification of DNA by glucose 6-phosphate induces DNA rearrangements in an Escherichia coli plasmid.

Reducing sugars such as glucose or glucose 6-phosphate (Glc-6-P) have been shown previously to modify the amino groups of nucleotides and single-stranded DNA. We have examined the mutagenic effect of Glc-6-P-induced lesions in the double-stranded DNA plasmid pBR322. Seventeen mutants of the Ampr Tet...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Bucala, R, Model, P, Russel, M, Cerami, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1985
Schlagworte:
Research Article
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390931/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3866232/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8439
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