Modification of DNA by glucose 6-phosphate induces DNA rearrangements in an Escherichia coli plasmid.
Reducing sugars such as glucose or glucose 6-phosphate (Glc-6-P) have been shown previously to modify the amino groups of nucleotides and single-stranded DNA. We have examined the mutagenic effect of Glc-6-P-induced lesions in the double-stranded DNA plasmid pBR322. Seventeen mutants of the Ampr Tet...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1985
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3866232/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8439 |
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