A Novel Acylaminoimidazole Derivative, WN1316, Alleviates Disease Progression via Suppression of Glial Inflammation in ALS Mouse Model

Amyotrophic lateral sclerosis (ALS) is an adult-onset motor neuron degenerative disease. Given that oxidative stress and resulting chronic neuronal inflammation are thought to be central pathogenic, anti-oxidative agents and modulators of neuronal inflammation could be potential therapies for ALS. W...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tanaka, Kazunori, Kanno, Takuya, Yanagisawa, Yoshiko, Yasutake, Kaori, Inoue, Satoshi, Hirayama, Noriaki, Ikeda, Joh-E
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909264/
https://ncbi.nlm.nih.gov/pubmed/24498180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087728
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